Javad Nazarian Selected Research

dipinacoline glutamate

1/2022	Characteristics of patients ≥10 years of age with diffuse intrinsic pontine glioma: a report from the International DIPG/DMG Registry.
1/2021	Preclinical and clinical evaluation of German-sourced ONC201 for the treatment of H3K27M-mutant diffuse intrinsic pontine glioma.
1/2021	Mesenchymal Stem Cells Successfully Deliver Oncolytic Virotherapy to Diffuse Intrinsic Pontine Glioma.
12/2020	Mass cytometry detects H3.3K27M-specific vaccine responses in diffuse midline glioma.
11/2020	Histone tail analysis reveals H3K36me2 and H4K16ac as epigenetic signatures of diffuse intrinsic pontine glioma.
5/2020	Addition of Multimodal Immunotherapy to Combination Treatment Strategies for Children with DIPG: A Single Institution Experience.
1/2020	Pharmacologic inhibition of lysine-specific demethylase 1 as a therapeutic and immune-sensitization strategy in pediatric high-grade glioma.
12/2019	Histone Variant and Cell Context Determine H3K27M Reprogramming of the Enhancer Landscape and Oncogenic State.
10/2019	A pilot precision medicine trial for children with diffuse intrinsic pontine glioma-PNOC003: A report from the Pacific Pediatric Neuro-Oncology Consortium.
1/2019	Identification of Novel RAS Signaling Therapeutic Vulnerabilities in Diffuse Intrinsic Pontine Gliomas.

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Javad Nazarian Research Topics

Disease

40	Neoplasms (Cancer) 01/2022 - 06/2008
24	Diffuse Intrinsic Pontine Glioma 01/2022 - 05/2012
18	Brain Neoplasms (Brain Tumor) 12/2021 - 05/2012
16	Glioma (Gliomas) 01/2022 - 06/2008
4	Medulloblastoma 01/2021 - 05/2015
3	Glioblastoma (Glioblastoma Multiforme) 01/2022 - 06/2014
3	Brain Stem Neoplasms (Brain Stem Tumor) 01/2021 - 01/2014
2	Ependymoma 10/2021 - 12/2020
2	Carcinogenesis 12/2020 - 04/2016
1	Craniopharyngioma (Craniopharyngiomas) 12/2020
1	Typical Teratoid Rhabdoid Tumor 12/2020
1	Ganglioglioma 12/2020
1	Circulating Neoplastic Cells 05/2020
1	Hyperthermia 05/2020
1	Wilms Tumor (Wilm's Tumor) 01/2019
1	Neuroblastoma 01/2018
1	Melanoma (Melanoma, Malignant) 02/2016
1	Central Nervous System Neoplasms 02/2016
1	Fibrosis (Cirrhosis) 10/2014
1	Adenoma (Adenomas) 01/2011
1	Leukoencephalopathies 02/2008
1	Vanishing White Matter Leukodystrophy with Ovarian Failure 02/2008

Drug/Important Bio-Agent (IBA)

28	dipinacoline glutamateIBA 01/2022 - 05/2012
8	Proteins (Proteins, Gene)FDA Link 01/2019 - 06/2008
7	Histones (Histone)IBA 11/2020 - 01/2011
3	VaccinesIBA 01/2022 - 05/2020
3	Biomarkers (Surrogate Marker)IBA 12/2021 - 06/2008
3	RNA (Ribonucleic Acid)IBA 10/2021 - 10/2019
3	Biological ProductsIBA 01/2021 - 07/2016
3	Messenger RNA (mRNA)IBA 05/2020 - 01/2014
3	Lysine (L-Lysine)FDA Link 01/2020 - 06/2014
2	TIC10 compoundIBA 12/2021 - 01/2021
2	Membrane Proteins (Integral Membrane Proteins)IBA 01/2021 - 02/2016
2	Phosphotransferases (Kinase)IBA 12/2020 - 01/2017
1	Neurofibromin 1 (Neurofibromin)IBA 01/2022
1	Protein Isoforms (Isoforms)IBA 01/2022
1	ONC206IBA 12/2021
1	Peptide Hydrolases (Proteases)FDA Link 12/2021
1	Metformin (Glucophage)FDA LinkGeneric 10/2021
1	Tricarboxylic AcidsIBA 10/2021
1	Hypoglycemic Agents (Hypoglycemics)IBA 10/2021
1	SurvivinIBA 01/2021
1	DNA (Deoxyribonucleic Acid)IBA 01/2021
1	romidepsin (FK228)FDA Link 01/2021
1	quisinostatIBA 01/2021
1	rebastinibIBA 01/2020
1	Methionine (L-Methionine)FDA Link 12/2019
1	Phosphoprotein Phosphatases (Phosphatases, Protein)IBA 01/2019
1	Cell-Free Nucleic AcidsIBA 01/2019
1	AntigensIBA 01/2019
1	NAD (NADH)IBA 01/2019
1	Conditioned Culture MediaIBA 01/2019
1	WT1 ProteinsIBA 01/2019
1	Nicotinamide PhosphoribosyltransferaseIBA 01/2019
1	Complement System Proteins (Complement)IBA 01/2018
1	Pharmaceutical PreparationsIBA 02/2017
1	Dexamethasone (Maxidex)FDA LinkGeneric 02/2017
1	VBP15 compoundIBA 02/2017
1	CytokinesIBA 02/2017
1	SteroidsIBA 02/2017
1	TOR Serine-Threonine KinasesIBA 01/2017
1	Mechanistic Target of Rapamycin Complex 1IBA 01/2017
1	Chondroitin Sulfate ProteoglycansIBA 02/2016
1	Proteoglycans (Proteoglycan)IBA 02/2016
1	ChondroitinIBA 02/2016
1	chondroitin sulfate proteoglycan 4IBA 02/2016
1	Azacitidine (5 Azacytidine)FDA Link 05/2015
1	MethyltransferasesIBA 05/2015
1	Transforming Growth Factors (Transforming Growth Factor)IBA 10/2014
1	5-Methylcytosine (5 Methylcytosine)IBA 06/2014
1	5-hydroxymethylcytosineIBA 06/2014
1	ManganeseIBA 01/2014
1	ferric ferrocyanide (Prussian blue)FDA Link 01/2014
1	NestinIBA 09/2013
1	CateninsIBA 09/2013
1	Butyrates (Butyrate)IBA 01/2011
1	perifosineIBA 03/2010
1	ParaffinIBA 06/2008
1	Peptides (Polypeptides)IBA 06/2008
1	Formaldehyde (Formol)FDA Link 06/2008
1	Eukaryotic Initiation Factor-2B (Eukaryotic Initiation Factor 2B)IBA 02/2008

Therapy/Procedure

14	Therapeutics 01/2021 - 05/2014
2	Precision Medicine 01/2022 - 10/2019
2	Immunotherapy 12/2020 - 01/2019
1	Oncolytic Virotherapy 01/2021
1	Molecular Targeted Therapy 05/2020
1	Drug Therapy (Chemotherapy) 05/2020
1	Radiotherapy 12/2018
1	Transplantation 01/2014